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Chromatin condensation via the condensin II complex is required for peripheral T-cell quiescence
Naive T cells encountering their cognate antigen become activated and acquire the ability to proliferate in response to cytokines. Stat5 is an essential component in this response. We demonstrate that Stat5 cannot access DNA in naive T cells and acquires this ability only after T-cell receptor (TCR)...
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| 主要な著者: | , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Nature Publishing Group
2011
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3025460/ https://ncbi.nlm.nih.gov/pubmed/21169989 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2010.314 |
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