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Chromatin condensation via the condensin II complex is required for peripheral T-cell quiescence
Naive T cells encountering their cognate antigen become activated and acquire the ability to proliferate in response to cytokines. Stat5 is an essential component in this response. We demonstrate that Stat5 cannot access DNA in naive T cells and acquires this ability only after T-cell receptor (TCR)...
Kaydedildi:
| Asıl Yazarlar: | , , , |
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| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
Nature Publishing Group
2011
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3025460/ https://ncbi.nlm.nih.gov/pubmed/21169989 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2010.314 |
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