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Hematopoietic Cyclooxygenase-2 Deficiency Increases Adipose Tissue Inflammation and Adiposity in Obesity
OBJECTIVE: Adipose tissue (AT) macrophages mediate AT inflammation in obesity and cyclooxygenase-2 (COX-2) is a major inflammatory gene. We hypothesized that deletion of hematopoietic COX-2 will inhibit AT inflammation in obesity. DESIGN AND METHODS: Lethally irradiated wild type (WT) mice were inje...
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| Veröffentlicht in: | Obesity (Silver Spring) |
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| Hauptverfasser: | , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2015
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6368065/ https://ncbi.nlm.nih.gov/pubmed/26316178 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/oby.21184 |
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