Attenuation of STAT3 Phosphorylation Promotes Apoptosis and Chemosensitivity in Human Osteosarcoma Induced by Raddeanin A

Osteosarcoma (OS) is the most common primary bone malignancy in adolescents. One major obstacle for current OS treatment is drug-resistance. Raddeanin A (RA), an oleanane-type triterpenoid saponin, exerts anti-tumor effects in several tumor models, but the effect of RA in human drug-resistant OS rem...

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Detalhes bibliográficos
Publicado no:Int J Biol Sci
Main Authors: Wang, Zhuoying, Wang, Chongren, Zuo, Dongqing, Zhang, Tao, Yin, Fei, Zhou, Zifei, Wang, Hongsheng, Xu, Jing, Mao, Min, Wang, Gangyang, Hua, Yingqi, Sun, Wei, Cai, Zhengdong
Formato: Artigo
Idioma:Inglês
Publicado em: Ivyspring International Publisher 2019
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6367581/
https://ncbi.nlm.nih.gov/pubmed/30745853
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/ijbs.30168
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