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NDRG1 inhibition sensitizes osteosarcoma cells to combretastatin A-4 through targeting autophagy
Combretastatin A-4 (CA-4), a tubulin-depolymerizing agent, shows promising antitumor efficacy and has been under several clinical trials in solid tumors for 10 years. Autophagy has an important pro-survival role in cancer therapy, thus targeting autophagy may improve the efficacy of antitumor agents...
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| 出版年: | Cell Death Dis |
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| 主要な著者: | , , , , , , , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Nature Publishing Group
2017
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5636982/ https://ncbi.nlm.nih.gov/pubmed/28906492 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2017.438 |
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