Differentially expressed gene networks, biomarkers, long noncoding RNAs, and shared responses with cocaine identified in the midbrains of human opioid abusers

Opioid abuse is now the most common cause of accidental death in the US. Although opioids and most other drugs of abuse acutely increase signaling mediated by midbrain dopamine (DA)-synthesizing neurons, little is known about long-lasting changes in DA cells that may contribute to continued opioid a...

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Détails bibliographiques
Publié dans:Sci Rep
Auteurs principaux: Saad, Manal H., Rumschlag, Matthew, Guerra, Michael H., Savonen, Candace L., Jaster, Alaina M., Olson, Philip D., Alazizi, Adnan, Luca, Francesca, Pique-Regi, Roger, Schmidt, Carl J., Bannon, Michael J.
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group UK 2019
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6367337/
https://ncbi.nlm.nih.gov/pubmed/30733491
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-38209-8
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