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Differentially expressed gene networks, biomarkers, long noncoding RNAs, and shared responses with cocaine identified in the midbrains of human opioid abusers

Opioid abuse is now the most common cause of accidental death in the US. Although opioids and most other drugs of abuse acutely increase signaling mediated by midbrain dopamine (DA)-synthesizing neurons, little is known about long-lasting changes in DA cells that may contribute to continued opioid a...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Saad, Manal H., Rumschlag, Matthew, Guerra, Michael H., Savonen, Candace L., Jaster, Alaina M., Olson, Philip D., Alazizi, Adnan, Luca, Francesca, Pique-Regi, Roger, Schmidt, Carl J., Bannon, Michael J.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6367337/
https://ncbi.nlm.nih.gov/pubmed/30733491
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-38209-8
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