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Structure of the post-translational protein translocation machinery of the ER membrane
Many proteins must translocate through the protein-conducting Sec61 channel in the eukaryotic endoplasmic reticulum membrane or the SecY channel in the prokaryotic plasma membrane(1,2). Proteins with hydrophobic signal sequences are first recognized by the signal recognition particle (SRP)(3,4) and...
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| Veröffentlicht in: | Nature |
|---|---|
| Hauptverfasser: | , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2018
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6367035/ https://ncbi.nlm.nih.gov/pubmed/30644436 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41586-018-0856-x |
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