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Preserving the membrane barrier for small molecules during bacterial protein translocation

Many proteins are translocated through the SecY channel in bacteria and archaea, and the related Sec61 channel in eukaryotes(1). The channel has an hourglass shape with a narrow constriction approximately halfway across the membrane, formed by a pore ring of amino acids(2). While the cytoplasmic cav...

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Autori principali: Park, Eunyong, Rapoport, Tom A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2011
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3093665/
https://ncbi.nlm.nih.gov/pubmed/21562565
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature10014
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