TRPS1 Is a Lineage-Specific Transcriptional Dependency in Breast Cancer

Perturbed epigenomic programs play key roles in tumorigenesis, and chromatin modulators are candidate therapeutic targets in various human cancer types. To define singular and shared dependencies on DNA and histone modifiers and transcription factors in poorly differentiated adult and pediatric canc...

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Publicado no:Cell Rep
Main Authors: Witwicki, Robert M., Ekram, Muhammad B., Qiu, Xintao, Janiszewska, Michalina, Shu, Shaokun, Kwon, Mijung, Trinh, Anne, Frias, Elizabeth, Ramadan, Nadire, Hoffman, Greg, Yu, Kristine, Xie, Yingtian, McAllister, Gregory, McDonald, Rob, Golji, Javad, Schlabach, Michael, deWeck, Antoine, Keen, Nicholas, Chan, Ho Man, Ruddy, David, Rejtar, Tomas, Sovath, Sosathya, Silver, Serena, Sellers, William R., Jagani, Zainab, Hogarty, Michael D., Roberts, Charles, Brown, Myles, Stegmaier, Kimberly, Long, Henry, Shivdasani, Ramesh A., Pellman, David, Polyak, Kornelia
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6366939/
https://ncbi.nlm.nih.gov/pubmed/30380416
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2018.10.023
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