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Nitro Sulfonyl Fluorides are a new pharmacophore for the development of antibiotics
The development of antibiotics against Gram-negative bacteria is a central problem in drug discovery. In this report, we demonstrate that aromatic sulfonyl fluorides with a nitro group in their ortho position have remarkable antibacterial activity and are active against drug-resistant pathogens, suc...
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| Pubblicato in: | Mol Syst Des Eng |
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| Autori principali: | , , , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2018
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6366622/ https://ncbi.nlm.nih.gov/pubmed/30740245 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/C8ME00011E |
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