Secreted IgD Amplifies Humoral T Helper-2 Responses by Binding Basophils Via Galectin-9 and CD44

B cells thwart antigenic aggressions by releasing immunoglobulin M (IgM), IgG, IgA and IgE, which deploy well-understood effector functions. In contrast, the role of secreted IgD remains mysterious. We found that some B cells generated IgD-secreting plasma cells following early exposure to external...

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Publicado no:Immunity
Main Authors: Shan, Meimei, Carrillo, Jorge, Yeste, Ada, Gutzeit, Cindy, Garzón, Daniel Segura, Walland, Cooper, Pybus, Marc, Grasset, Emilie K., Yeiser, A. John R., Matthews, Dean B., van de Veen, Willem, Comerma, Laura, He, Bing, Boonpiyathad, Tadech, Lee, Haekyung, Blanco, Julià, Osborne, Lisa C., Siracusa, Mark C., Akdis, Mübeccel, Artis, David, Mehandru, Saurabh, Sampson, Hugh A., Berin, M. Cecilia, Chen, Kang, Cerutti, Andrea
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6366614/
https://ncbi.nlm.nih.gov/pubmed/30291028
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2018.08.013
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