Secreted IgD Amplifies Humoral T Helper-2 Responses by Binding Basophils Via Galectin-9 and CD44

B cells thwart antigenic aggressions by releasing immunoglobulin M (IgM), IgG, IgA and IgE, which deploy well-understood effector functions. In contrast, the role of secreted IgD remains mysterious. We found that some B cells generated IgD-secreting plasma cells following early exposure to external...

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Bibliografiset tiedot
Julkaisussa:Immunity
Päätekijät: Shan, Meimei, Carrillo, Jorge, Yeste, Ada, Gutzeit, Cindy, Garzón, Daniel Segura, Walland, Cooper, Pybus, Marc, Grasset, Emilie K., Yeiser, A. John R., Matthews, Dean B., van de Veen, Willem, Comerma, Laura, He, Bing, Boonpiyathad, Tadech, Lee, Haekyung, Blanco, Julià, Osborne, Lisa C., Siracusa, Mark C., Akdis, Mübeccel, Artis, David, Mehandru, Saurabh, Sampson, Hugh A., Berin, M. Cecilia, Chen, Kang, Cerutti, Andrea
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2018
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Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC6366614/
https://ncbi.nlm.nih.gov/pubmed/30291028
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2018.08.013
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