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Obesity alters phosphoramide mustard-induced ovarian DNA repair in mice(†)

Phosphoramide mustard (PM) destroys rapidly dividing cells and activates the DNA double strand break marker, γH2AX, and DNA repair in rat granulosa cells and neonatal ovaries. The effects of PM exposure on DNA damage and activation of DNA damage repair in lean and obese female mice were investigated...

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Detalhes bibliográficos
Publicado no:Biol Reprod
Main Authors: Ganesan, Shanthi, Nteeba, Jackson, Madden, Jill A., Keating, Aileen F.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6366544/
https://ncbi.nlm.nih.gov/pubmed/28203708
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1095/biolreprod.116.143800
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