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Obesity alters phosphoramide mustard-induced ovarian DNA repair in mice(†)

Phosphoramide mustard (PM) destroys rapidly dividing cells and activates the DNA double strand break marker, γH2AX, and DNA repair in rat granulosa cells and neonatal ovaries. The effects of PM exposure on DNA damage and activation of DNA damage repair in lean and obese female mice were investigated...

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Publicado en:Biol Reprod
Autores principales: Ganesan, Shanthi, Nteeba, Jackson, Madden, Jill A., Keating, Aileen F.
Formato: Artigo
Lenguaje:Inglês
Publicado: Oxford University Press 2017
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6366544/
https://ncbi.nlm.nih.gov/pubmed/28203708
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1095/biolreprod.116.143800
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