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Inhibition of Stat3‐mediated astrogliosis ameliorates pathology in an Alzheimer's disease model

Reactive astrogliosis is a hallmark of Alzheimer's disease (AD), but its role for disease initiation and progression has remained incompletely understood. We here show that the transcription factor Stat3 (signal transducer and activator of transcription 3), a canonical inducer of astrogliosis,...

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Detalhes bibliográficos
Publicado no:EMBO Mol Med
Main Authors: Reichenbach, Nicole, Delekate, Andrea, Plescher, Monika, Schmitt, Franziska, Krauss, Sybille, Blank, Nelli, Halle, Annett, Petzold, Gabor C
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6365929/
https://ncbi.nlm.nih.gov/pubmed/30617153
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/emmm.201809665
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