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hsa-miR-3177-5p and hsa-miR-3178 Inhibit 5-HT1A Expression by Binding the 3′-UTR Region in vitro

Abnormal expression of the 5-HT1A receptor, which is encoded by the HTR1A gene, leads to susceptibilities to neuropsychiatric disorders such as depression, anxiety, and schizophrenia. miRNAs regulate gene expression by recognizing the 3′-UTR region of mRNA. This study evaluated the miRNAs that might...

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Detalles Bibliográficos
Publicado en:Front Mol Neurosci
Main Authors: Wu, Xue, Ding, Mei, Liu, Yi, Xia, Xi, Xu, Feng-ling, Yao, Jun, Wang, Bao-jie
Formato: Artigo
Idioma:Inglês
Publicado: Frontiers Media S.A. 2019
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6365703/
https://ncbi.nlm.nih.gov/pubmed/30766477
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnmol.2019.00013
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