Hsa-miR-24-3p Increases Nasopharyngeal Carcinoma Radiosensitivity by Targeting Both the 3’UTR and 5’UTR of Jab1/CSN5

Radiotherapy is the standard therapy for nasopharyngeal carcinoma (NPC); however, radioresistance can hinder successful treatment. Here, we report that miR-24 acts as a tumor suppressor and radiosensitizer in NPC cells and xenografts by targeting Jab1/CSN5. Although accumulating evidence has shown t...

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Detalhes bibliográficos
Publicado no:Oncogene
Main Authors: Wang, Sumei, Pan, Yunbao, Zhang, Rong, Xu, Tao, Wu, Wanyin, Wang, Chunhua, Huang, Hecheng, Calin, George A., Yang, Huiling, Claret, Francois X.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5102828/
https://ncbi.nlm.nih.gov/pubmed/27157611
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2016.147
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