Epigenetic regulation of NfatC1 transcription and osteoclastogenesis by nicotinamide phosphoribosyl transferase in the pathogenesis of arthritis

Nicotinamide phosphoribosyltransferase (NAMPT) functions in NAD synthesis, apoptosis, and inflammation. Dysregulation of NAMPT has been associated with several inflammatory diseases, including rheumatoid arthritis (RA). The purpose of this study was to investigate NAMPT’s role in arthritis using mou...

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Detalhes bibliográficos
Publicado no:Cell Death Discov
Main Authors: Li, Xuanan, Islam, Shamima, Xiong, Min, Nsumu, Ndona N., Lee, Mark W., Zhang, Li Qin, Ueki, Yasuyoshi, Heruth, Daniel P., Lei, Guanghua, Ye, Shui Qing
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6365567/
https://ncbi.nlm.nih.gov/pubmed/30774990
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41420-018-0134-6
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