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Robust and efficient knock-in in embryonic stem cells and early-stage embryos of the common marmoset using the CRISPR-Cas9 system

Genome editing technology greatly facilitates the genetic modification of various cells and animals. The common marmoset (Callithrix jacchus), a small non-human primate which exhibits high reproductive efficiency, is a widely used animal model in biomedical research. Developing genome editing techni...

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Dades bibliogràfiques
Publicat a:Sci Rep
Autors principals: Yoshimatsu, Sho, Okahara, Junko, Sone, Takefumi, Takeda, Yuta, Nakamura, Mari, Sasaki, Erika, Kishi, Noriyuki, Shiozawa, Seiji, Okano, Hideyuki
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2019
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6365532/
https://ncbi.nlm.nih.gov/pubmed/30728412
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-37990-w
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