Pathogenesis of Atypical Hemolytic Uremic Syndrome

Atypical hemolytic uremic syndrome (aHUS) is a type of thrombotic microangiopathy (TMA) defined by thrombocytopenia, microangiopathic hemolytic anemia, and renal failure. aHUS is caused by uncontrolled complement activation in the alternative pathway (AP). A variety of genetic defects in complement-...

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Podrobná bibliografie
Vydáno v:J Atheroscler Thromb
Hlavní autoři: Yoshida, Yoko, Kato, Hideki, Ikeda, Yoichiro, Nangaku, Masaomi
Médium: Artigo
Jazyk:Inglês
Vydáno: Japan Atherosclerosis Society 2019
Témata:
Review
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6365154/
https://ncbi.nlm.nih.gov/pubmed/30393246
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.5551/jat.RV17026
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