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Pathogenesis of Atypical Hemolytic Uremic Syndrome

Atypical hemolytic uremic syndrome (aHUS) is a type of thrombotic microangiopathy (TMA) defined by thrombocytopenia, microangiopathic hemolytic anemia, and renal failure. aHUS is caused by uncontrolled complement activation in the alternative pathway (AP). A variety of genetic defects in complement-...

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Detalhes bibliográficos
Publicado no:J Atheroscler Thromb
Main Authors: Yoshida, Yoko, Kato, Hideki, Ikeda, Yoichiro, Nangaku, Masaomi
Formato: Artigo
Idioma:Inglês
Publicado em: Japan Atherosclerosis Society 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6365154/
https://ncbi.nlm.nih.gov/pubmed/30393246
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.5551/jat.RV17026
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