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Lentiviral transduction of mammalian cells for fast, scalable and high-level production of soluble and membrane proteins

Structural, biochemical and biophysical studies of eukaryotic soluble and membrane proteins require their production to milligram quantities. Although large-scale protein expression strategies based on transient or stable transfection of mammalian cells are well established, they are associated with...

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Detalhes bibliográficos
Publicado no:Nat Protoc
Main Authors: Elegheert, Jonathan, Behiels, Ester, Bishop, Benjamin, Scott, Suzanne, Woolley, Rachel E., Griffiths, Samuel C., Byrne, Eamon F. X., Chang, Veronica T., Stuart, David I., Jones, E. Yvonne, Siebold, Christian, Aricescu, A. Radu
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6364805/
https://ncbi.nlm.nih.gov/pubmed/30455477
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41596-018-0075-9
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