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Therapeutic protein transduction of mammalian cells and mice by nucleic acid-free lentiviral nanoparticles
The straightforward production and dose-controlled administration of protein therapeutics remain major challenges for the biopharmaceutical manufacturing and gene therapy communities. Transgenes linked to HIV-1-derived vpr and pol-based protease cleavage (PC) sequences were co-produced as chimeric f...
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| Main Authors: | , , , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Oxford University Press
2006
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1356536/ https://ncbi.nlm.nih.gov/pubmed/16449199 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gnj014 |
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