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An engineered mammalian band-pass network

Gene expression circuitries, which enable cells to detect precise levels within a morphogen concentration gradient, have a pivotal impact on biological processes such as embryonic pattern formation, paracrine and autocrine signalling, and cellular migration. We present the rational synthesis of a sy...

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Bibliographic Details
Main Authors: Greber, David, Fussenegger, Martin
Format: Artigo
Language:Inglês
Published: Oxford University Press 2010
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2952875/
https://ncbi.nlm.nih.gov/pubmed/20693530
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkq671
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