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Evaluation of in-vitro cytotoxic effect of 5-FU loaded-chitosan nanoparticles against spheroid models

PURPOSE: The studies investigate the anticancer activity of 5-fluorouracil (5-FU)-hyaluronidase (Hase) enzyme-loaded chitosan nanoparticles (5-FUChnps) using three-dimensional (3D) spheroid HCT-116 culture. Hase-loaded nanoparticles (Chnps) have recently been used to improve the efficacy of chemothe...

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Detalles Bibliográficos
Publicado en:J Nat Sci
Main Authors: Smith, Taylor, Affram, Kevin, Bulumko, Errol, Agyare, Edward
Formato: Artigo
Idioma:Inglês
Publicado: 2018
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6364702/
https://ncbi.nlm.nih.gov/pubmed/30740523
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