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HDAC3 protects DP thymocytes from P2X7 receptor-induced cell death

Intricate life-versus-death decisions are programmed during T cell development, and the regulatory mechanisms that coordinate their activation and repression are still under investigation. Here, HDAC3-deficient DP thymocytes exhibit a severe decrease in numbers. The thymic cortex is rich in ATP, whi...

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Vydáno v:J Immunol
Hlavní autoři: Philips, Rachael L., McCue, Shaylene A., Rajcula, Matthew J., Shapiro, Virginia S.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2019
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6363889/
https://ncbi.nlm.nih.gov/pubmed/30626694
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1801438
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