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Children with neutrophil-predominant severe asthma have pro-inflammatory neutrophils with enhanced survival and impaired clearance

BACKGROUND: Airway neutrophils are abundant in some children with severe asthma, but their functions are poorly understood. OBJECTIVE: We hypothesized that the inflammatory airway environment of children with neutrophil-predominant severe asthma promotes neutrophil survival and disrupts neutrophil-a...

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Detalles Bibliográficos
Publicado en:J Allergy Clin Immunol Pract
Main Authors: Grunwell, Jocelyn R., Stephenson, Susan T., Tirouvanziam, Rabindra, Brown, Lou Ann S., Brown, Milton R., Fitzpatrick, Anne M.
Formato: Artigo
Idioma:Inglês
Publicado: 2018
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6363859/
https://ncbi.nlm.nih.gov/pubmed/30193935
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jaip.2018.08.024
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