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Can protein expression be regulated by modulation of tRNA modifications profiles?

tRNAs are the central adaptor molecules in translation. Their decoding properties are influenced by post-transcriptional modifications, particularly in the critical anticodon-stem-loop (ASL) region. Synonymous codon choice, also called codon usage bias, affects both translation efficiency and accura...

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Bibliografske podrobnosti
izdano v:Biochemistry
Main Authors: Pollo-Oliveira, Leticia, de Crécy-Lagard, Valérie
Format: Artigo
Jezik:Inglês
Izdano: 2018
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6363828/
https://ncbi.nlm.nih.gov/pubmed/30511849
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.biochem.8b01035
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