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Albumin-linked prostate-specific antigen-activated thapsigargin- and niclosamide-based molecular grenades targeting the microenvironment in metastatic castration-resistant prostate cancer

Localized prostate cancer is curable via annihilation of the entire cancer neighborhood by surgery or local radiation. Unfortunately, once metastatic, no available therapy is curative. The vast majority will die despite aggressive systemic combinational androgen-ablation therapies. Thus, there is an...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Asian J Urol
Prif Awduron: Akinboye, Emmanuel S., Brennen, W. Nathaniel, Denmeade, Samuel R., Isaacs, John T.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Second Military Medical University 2019
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6363604/
https://ncbi.nlm.nih.gov/pubmed/30775253
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajur.2018.11.004
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