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2-fluoro-5-maleimidobenzoic acid-linked albumin drug (MAD) delivery for selective systemic targeting of metastatic prostate cancer

BACKGROUND: The SH-group at Cys-34 of human serum albumin (HSA) is a unique and accessible functional group that can be exploited for efficient linkage of a maleimide containing cytotoxic drug derivative to albumin. The specific maleimide chemistry used for production of the maleimide-linked albumin...

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Bibliografske podrobnosti
izdano v:Prostate
Main Authors: Akinboye, Emmanuel S., Rogers, Oliver C., Isaacs, John T.
Format: Artigo
Jezik:Inglês
Izdano: 2018
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6404533/
https://ncbi.nlm.nih.gov/pubmed/29572902
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pros.23494
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