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Safety, tolerability and impact on viral reservoirs of the addition to antiretroviral therapy of ABX464, an investigational antiviral drug, in individuals living with HIV-1: a Phase IIa randomised controlled study

OBJECTIVES: To assess the safety and tolerability as well as antiretroviral impact of ABX464, an oral investigational drug with a novel mechanism of HIV-1 inhibition (ClinicalTrials.gov NCT02735863). METHODS: Randomised, double-blind, placebo-controlled, Phase IIa study in individuals living with HI...

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Dettagli Bibliografici
Pubblicato in:J Virus Erad
Autori principali: Rutsaert, Sofie, Steens, Jean-Marc, Gineste, Paul, Cole, Basiel, Kint, Sam, Barrett, P Noel, Tazi, Jamal, Scherrer, Didier, Ehrlich, Hartmut J, Vandekerckhove, Linos
Natura: Artigo
Lingua:Inglês
Pubblicazione: Mediscript Ltd 2019
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6362909/
https://ncbi.nlm.nih.gov/pubmed/30800421
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