A conserved CAF40-binding motif in metazoan NOT4 mediates association with the CCR4–NOT complex

The multisubunit CCR4–NOT mRNA deadenylase complex plays important roles in the posttranscriptional regulation of gene expression. The NOT4 E3 ubiquitin ligase is a stable component of the CCR4–NOT complex in yeast but does not copurify with the human or Drosophila melanogaster complex. Here we show...

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Bibliografiske detaljer
Udgivet i:Genes Dev
Main Authors: Keskeny, Csilla, Raisch, Tobias, Sgromo, Annamaria, Igreja, Cátia, Bhandari, Dipankar, Weichenrieder, Oliver, Izaurralde, Elisa
Format: Artigo
Sprog:Inglês
Udgivet: Cold Spring Harbor Laboratory Press 2019
Fag:
Research Paper
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6362812/
https://ncbi.nlm.nih.gov/pubmed/30692204
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.320952.118
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