Activation and Proliferation of PD-1(+) Kidney Double-Negative T Cells Is Dependent on Nonclassical MHC Proteins and IL-2

BACKGROUND: CD4(−) CD8(−) double-negative (DN) αβ T cells with innate-like properties represent a significant component of T cells in human and mouse kidneys. They spontaneously proliferate in the steady state and protect against ischemic AKI. However, the mechanisms regulating DN T cell homeostasis...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:J Am Soc Nephrol
Egile Nagusiak: Sadasivam, Mohanraj, Noel, Sanjeev, Lee, Sul A., Gong, Jing, Allaf, Mohamad E., Pierorazio, Phillip, Rabb, Hamid, Hamad, Abdel Rahim A.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society of Nephrology 2019
Gaiak:
Basic Research
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6362627/
https://ncbi.nlm.nih.gov/pubmed/30622155
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2018080815
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