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Activation and Proliferation of PD-1(+) Kidney Double-Negative T Cells Is Dependent on Nonclassical MHC Proteins and IL-2
BACKGROUND: CD4(−) CD8(−) double-negative (DN) αβ T cells with innate-like properties represent a significant component of T cells in human and mouse kidneys. They spontaneously proliferate in the steady state and protect against ischemic AKI. However, the mechanisms regulating DN T cell homeostasis...
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| Publicado no: | J Am Soc Nephrol |
|---|---|
| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society of Nephrology
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6362627/ https://ncbi.nlm.nih.gov/pubmed/30622155 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2018080815 |
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