EphB2-dependent signaling promotes neuronal excitotoxicity and inflammation in the acute phase of ischemic stroke

Local cerebral hypoperfusion causes ischemic stroke while driving multiple cell-specific responses including inflammation, glutamate-induced neurotoxicity mediated via NMDAR, edema formation and angiogenesis. Despite the relevance of these pathophysiological mechanisms for disease progression and ou...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Acta Neuropathol Commun
Main Authors: Ernst, Anne-Sophie, Böhler, Laura-Inés, Hagenston, Anna M., Hoffmann, Angelika, Heiland, Sabine, Sticht, Carsten, Bendszus, Martin, Hecker, Markus, Bading, Hilmar, Marti, Hugo H., Korff, Thomas, Kunze, Reiner
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2019
Teme:
Research
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6362601/
https://ncbi.nlm.nih.gov/pubmed/30722785
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40478-019-0669-7
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