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High-Field MRI Reveals a Drastic Increase of Hypoxia-Induced Microhemorrhages upon Tissue Reoxygenation in the Mouse Brain with Strong Predominance in the Olfactory Bulb

Human pathophysiology of high altitude hypoxic brain injury is not well understood and research on the underlying mechanisms is hampered by the lack of well-characterized animal models. In this study, we explored the evolution of brain injury by magnetic resonance imaging (MRI) and histological meth...

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Bibliografski detalji
Izdano u:PLoS One
Glavni autori: Hoffmann, Angelika, Kunze, Reiner, Helluy, Xavier, Milford, David, Heiland, Sabine, Bendszus, Martin, Pham, Mirko, Marti, Hugo H.
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2016
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4749302/
https://ncbi.nlm.nih.gov/pubmed/26863147
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0148441
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