Striatal amyloid is associated with tauopathy and memory decline in familial Alzheimer’s disease

BACKGROUND: Autosomal dominant Alzheimer’s disease (ADAD) is distinguished from late-onset AD by early striatal amyloid-β deposition. To determine whether striatal Pittsburgh compound B (PiB)-PET measurements of amyloid-β can help predict disease severity in ADAD, we compared relationships of striat...

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Detalhes bibliográficos
Publicado no:Alzheimers Res Ther
Main Authors: Hanseeuw, Bernard J., Lopera, Francisco, Sperling, Reisa A., Norton, Daniel J., Guzman-Velez, Edmarie, Baena, Ana, Pardilla-Delgado, Enmanuelle, Schultz, Aaron P., Gatchel, Jennifer, Jin, David, Chen, Kewei, Reiman, Eric M., Johnson, Keith A., Quiroz, Yakeel T.
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2019
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6362587/
https://ncbi.nlm.nih.gov/pubmed/30717814
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13195-019-0468-1
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