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Associations between plasma neurofilament light, in vivo brain pathology and cognition in non-demented individuals with autosomal- dominant Alzheimer’s disease

BACKGROUND: Neurofilament light (NfL) is a promising biomarker of early neurodegeneration in Alzheimer’s disease (AD). We examined whether plasma NfL was associated with in vivo amyloid-β and tau, and cognitive performance in non-demented Presenilin-1 (PSEN1) E280A mutation carriers. METHODS: Twenty...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Alzheimers Dement
Päätekijät: Guzmán-Vélez, Edmarie, Zetterberg, Henrik, Fox-Fuller, Joshua T., Vila-Castelar, Clara, Sanchez, Justin S., Baena, Ana, Garcia-Ospina, Gloria, Aguillon, David, Pardilla-Delgado, Enmanuelle, Gatchel, Jennifer, Sperling, Reisa A., Johnson, Keith, Reiman, Eric M., Blennow, Kaj, Lopera, Francisco, Quiroz, Yakeel T.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2021
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC8158654/
https://ncbi.nlm.nih.gov/pubmed/33527648
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/alz.12248
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