Epigenetic control of hypersensitivity in chronic inflammatory pain by the de novo DNA methyltransferase Dnmt3a2

Chronic pain is a pathological manifestation of neuronal plasticity supported by altered gene transcription in spinal cord neurons that results in long-lasting hypersensitivity. Recently, the concept that epigenetic regulators might be important in pathological pain has emerged, but a clear understa...

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Veröffentlicht in:Mol Pain
Hauptverfasser: Oliveira, Ana MM, Litke, Christian, Paldy, Eszter, Hagenston, Anna M, Lu, Jianning, Kuner, Rohini, Bading, Hilmar, Mauceri, Daniela
Format: Artigo
Sprache:Inglês
Veröffentlicht: SAGE Publications 2019
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6362517/
https://ncbi.nlm.nih.gov/pubmed/30638145
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1744806919827469
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