Virus-specific memory T cells populate tumors and can be repurposed for tumor immunotherapy

The immunosuppressive tumor microenvironment limits the success of current immunotherapies. The host retains memory T cells specific for previous infections throughout the entire body that are capable of executing potent and immediate immunostimulatory functions. Here we show that virus-specific mem...

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Библиографические подробности
Опубликовано в: :Nat Commun
Главные авторы: Rosato, Pamela C., Wijeyesinghe, Sathi, Stolley, J. Michael, Nelson, Christine E., Davis, Rachel L., Manlove, Luke S., Pennell, Christopher A., Blazar, Bruce R., Chen, Clark C., Geller, Melissa A., Vezys, Vaiva, Masopust, David
Формат: Artigo
Язык:Inglês
Опубликовано: Nature Publishing Group UK 2019
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Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6362136/
https://ncbi.nlm.nih.gov/pubmed/30718505
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-08534-1
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