Sphingosine 1 phosphate receptor-1 (S1P1) promotes tumor-associated regulatory T cell expansion: leading to poor survival in bladder cancer

Regulatory T cells (Tregs) represent an important contributor to cancer immune escape, but the molecular mechanism responsible for Treg expansion in tumors is heterogeneous and unclear. Here, we investigated the role of S1P1, a receptor of the bioactive lipid sphingosine 1-phosphate (S1P), in regula...

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Detalhes bibliográficos
Publicado no:Cell Death Dis
Main Authors: Liu, Yi-Na, Zhang, Han, Zhang, Lin, Cai, Ting-Ting, Huang, Dai-Jia, He, Jia, Ni, Huan-He, Zhou, Fang-Jian, Zhang, Xiao-Shi, Li, Jiang
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6362099/
https://ncbi.nlm.nih.gov/pubmed/30718502
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-018-1298-y
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