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Sphingosine-1-phosphate prevents permeability increases via activation of endothelial sphingosine-1-phosphate receptor 1 in rat venules

Sphingosine-1-phosphate (S1P) has been demonstrated to enhance endothelial barrier function in vivo and in vitro. However, different S1P receptor subtypes have been indicated to play different or even opposing roles in the regulation of vascular barrier function. This study aims to differentiate the...

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Autores principales: Zhang, Gengqian, Xu, Sulei, Qian, Yan, He, Pingnian
Formato: Artigo
Lenguaje:Inglês
Publicado: American Physiological Society 2010
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2993214/
https://ncbi.nlm.nih.gov/pubmed/20729401
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00462.2010
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