Caveolin-1 scaffolding domain promotes leukocyte adhesion by reduced basal endothelial nitric oxide-mediated ICAM-1 phosphorylation in rat mesenteric venules

Exogenously applied caveolin-1 scaffolding domain (CAV) has been shown to inhibit inflammatory mediator-induced nitric oxide (NO) production and NO-mediated increases in microvessel permeability. However, the effect of CAV on endothelial basal NO that prevents leukocyte adhesion remains unknown. Thi...

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Detalhes bibliográficos
Main Authors: Xu, Sulei, Zhou, Xueping, Yuan, Dong, Xu, Yanchun, He, Pingnian
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2013
Assuntos:
Vascular Biology and Microcirculation
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3840264/
https://ncbi.nlm.nih.gov/pubmed/24043249
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00382.2013
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