Orexin in the anxiety spectrum: association of a HCRTR1 polymorphism with panic disorder/agoraphobia, CBT treatment response and fear-related intermediate phenotypes

Preclinical studies point to a pivotal role of the orexin 1 (OX(1)) receptor in arousal and fear learning and therefore suggest the HCRTR1 gene as a prime candidate in panic disorder (PD) with/without agoraphobia (AG), PD/AG treatment response, and PD/AG-related intermediate phenotypes. Here, a mult...

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Λεπτομέρειες βιβλιογραφικής εγγραφής
Τόπος έκδοσης:Transl Psychiatry
Κύριοι συγγραφείς: Gottschalk, Michael G., Richter, Jan, Ziegler, Christiane, Schiele, Miriam A., Mann, Julia, Geiger, Maximilian J., Schartner, Christoph, Homola, György A., Alpers, Georg W., Büchel, Christian, Fehm, Lydia, Fydrich, Thomas, Gerlach, Alexander L., Gloster, Andrew T., Helbig-Lang, Sylvia, Kalisch, Raffael, Kircher, Tilo, Lang, Thomas, Lonsdorf, Tina B., Pané-Farré, Christiane A., Ströhle, Andreas, Weber, Heike, Zwanzger, Peter, Arolt, Volker, Romanos, Marcel, Wittchen, Hans-Ulrich, Hamm, Alfons, Pauli, Paul, Reif, Andreas, Deckert, Jürgen, Neufang, Susanne, Höfler, Michael, Domschke, Katharina
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: Nature Publishing Group UK 2019
Θέματα:
Article
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6361931/
https://ncbi.nlm.nih.gov/pubmed/30718541
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41398-019-0415-8
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