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Intrapleural Gene Therapy for Alpha-1 Antitrypsin Deficiency-Related Lung Disease

Alpha-1 antitrypsin deficiency (AATD) manifests primarily as early-onset emphysema caused by the destruction of the lung by neutrophil elastase due to low amounts of the serine protease inhibitor alpha-1 antitrypsin (AAT). The current therapy involves weekly intravenous infusions of AAT-derived from...

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Publicado en:Chronic Obstr Pulm Dis
Main Authors: Stiles, Katie M., Sondhi, Dolan, Kaminsky, Stephen M., De, Bishnu P., Rosenberg, Jonathan B., Crystal, Ronald G.
Formato: Artigo
Idioma:Inglês
Publicado: COPD Foundation Inc 2018
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6361473/
https://ncbi.nlm.nih.gov/pubmed/30723782
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15326/jcopdf.5.4.2017.0160
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