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Gene Therapy for Alpha-1 Antitrypsin Deficiency Lung Disease

Alpha-1 antitrypsin (AAT) deficiency, characterized by low plasma levels of the serine protease inhibitor AAT, is associated with emphysema secondary to insufficient protection of the lung from neutrophil proteases. Although AAT augmentation therapy with purified AAT protein is efficacious, it requi...

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Bibliografiska uppgifter
I publikationen:Ann Am Thorac Soc
Huvudupphovsmän: Chiuchiolo, Maria J., Crystal, Ronald G.
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Thoracic Society 2016
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5059492/
https://ncbi.nlm.nih.gov/pubmed/27564673
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1513/AnnalsATS.201506-344KV
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