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Gene Therapy for Alpha-1 Antitrypsin Deficiency Lung Disease
Alpha-1 antitrypsin (AAT) deficiency, characterized by low plasma levels of the serine protease inhibitor AAT, is associated with emphysema secondary to insufficient protection of the lung from neutrophil proteases. Although AAT augmentation therapy with purified AAT protein is efficacious, it requi...
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| Veröffentlicht in: | Ann Am Thorac Soc |
|---|---|
| Hauptverfasser: | , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
American Thoracic Society
2016
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5059492/ https://ncbi.nlm.nih.gov/pubmed/27564673 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1513/AnnalsATS.201506-344KV |
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