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Gene Therapy for Alpha-1 Antitrypsin Deficiency Lung Disease

Alpha-1 antitrypsin (AAT) deficiency, characterized by low plasma levels of the serine protease inhibitor AAT, is associated with emphysema secondary to insufficient protection of the lung from neutrophil proteases. Although AAT augmentation therapy with purified AAT protein is efficacious, it requi...

Täydet tiedot

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Bibliografiset tiedot
Julkaisussa:Ann Am Thorac Soc
Päätekijät: Chiuchiolo, Maria J., Crystal, Ronald G.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Thoracic Society 2016
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC5059492/
https://ncbi.nlm.nih.gov/pubmed/27564673
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1513/AnnalsATS.201506-344KV
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