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Peroxisome proliferator-activated receptor-β/δ inhibits human neuroblastoma cell tumorigenesis by inducing p53- and SOX2-mediated cell differentiation

Neuroblastoma is a common childhood cancer typically treated by inducing differentiation with retinoic acid (RA). Peroxisome proliferator-activated receptor-β/δ, (PPARβ/δ) is known to promote terminal differentiation of many cell types. In the present study, PPARβ/δ was overexpressed in three human...

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Detalhes bibliográficos
Publicado no:Mol Carcinog
Main Authors: Yao, Pei-Li, Chen, Liping, Dobrzański, Tomasz P., Zhu, Bokai, Kang, Boo-Hyon, Müller, Rolf, Gonzalez, Frank J., Peters, Jeffrey M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6361394/
https://ncbi.nlm.nih.gov/pubmed/27996177
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/mc.22607
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