Ligand activation of peroxisome proliferator-activated receptor β/δ (PPARβ/δ) inhibits chemically induced skin tumorigenesis

Peroxisome proliferator-activated receptor (PPAR)β/δ-null mice exhibit enhanced tumorigenesis in a two-stage chemical carcinogenesis model as compared with wild-type mice. Previous work showed that ligand activation of PPARβ/δ induces terminal differentiation and inhibits proliferation of primary ke...

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Detalhes bibliográficos
Main Authors: Bility, Moses T., Devlin-Durante, Meghann K., Blazanin, Nicholas, Glick, Adam B., Ward, Jerrold M., Kang, Boo Hyon, Kennett, Mary J., Gonzalez, Frank J., Peters, Jeffrey M.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2008
Assuntos:
Carcinogenesis
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2722866/
https://ncbi.nlm.nih.gov/pubmed/18799709
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/carcin/bgn219
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