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A neurodevelopmental TUBB2B β-tubulin mutation impairs Bim1 (yeast EB1)-dependent spindle positioning

Malformations of the human cerebral cortex can be caused by mutations in tubulins that associate to compose microtubules. Cerebral cortical folding relies on neuronal migration and on progenitor proliferation partly dictated by microtubule-dependent mitotic spindle positioning. A single amino acid c...

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Detalhes bibliográficos
Publicado no:Biol Open
Main Authors: Denarier, Eric, Brousse, Carine, Sissoko, Abdoulaye, Andrieux, Annie, Boscheron, Cécile
Formato: Artigo
Idioma:Inglês
Publicado em: The Company of Biologists Ltd 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6361202/
https://ncbi.nlm.nih.gov/pubmed/30674462
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/bio.038620
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