γ-Tubulin Ring Complexes and EB1 play antagonistic roles in microtubule dynamics and spindle positioning

γ-Tubulin is critical for microtubule (MT) assembly and organization. In metazoa, this protein acts in multiprotein complexes called γ-Tubulin Ring Complexes (γ-TuRCs). While the subunits that constitute γ-Tubulin Small Complexes (γ-TuSCs), the core of the MT nucleation machinery, are essential, mut...

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Bibliographic Details
Main Authors: Bouissou, Anaїs, Vérollet, Christel, de Forges, Hélène, Haren, Laurence, Bellaїche, Yohanns, Perez, Franck, Merdes, Andreas, Raynaud-Messina, Brigitte
Format: Artigo
Language:Inglês
Published: Blackwell Publishing Ltd 2014
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3989606/
https://ncbi.nlm.nih.gov/pubmed/24421324
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/embj.201385967
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