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An exonic splicing enhancer mutation in DUOX2 causes aberrant alternative splicing and severe congenital hypothyroidism in Bama pigs

Pigs share many similarities with humans in terms of anatomy, physiology and genetics, and have long been recognized as important experimental animals in biomedical research. Using an N-ethyl-N-nitrosourea (ENU) mutagenesis screen, we previously identified a large number of pig mutants, which could...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
הוצא לאור ב:Dis Model Mech
Main Authors: Cao, Chunwei, Zhang, Ying, Jia, Qitao, Wang, Xiao, Zheng, Qiantao, Zhang, Hongyong, Song, Ruigao, Li, Yongshun, Luo, Ailing, Hong, Qianlong, Qin, Guosong, Yao, Jing, Zhang, Nan, Wang, Yanfang, Wang, Hongmei, Zhou, Qi, Zhao, Jianguo
פורמט: Artigo
שפה:Inglês
יצא לאור: The Company of Biologists Ltd 2019
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC6361156/
https://ncbi.nlm.nih.gov/pubmed/30651277
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dmm.036616
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