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Hippo signaling promotes lung epithelial lineage commitment by curbing Fgf10 and β-catenin signaling

Organ growth and tissue homeostasis rely on the proliferation and differentiation of progenitor cell populations. In the developing lung, localized Fgf10 expression maintains distal Sox9-expressing epithelial progenitors and promotes basal cell differentiation in the cartilaginous airways. Mesenchym...

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Detalhes bibliográficos
Publicado no:Development
Main Authors: Volckaert, Thomas, Yuan, Tingting, Yuan, Jie, Boateng, Eistine, Hopkins, Seantel, Zhang, Jin-San, Thannickal, Victor J., Fässler, Reinhard, De Langhe, Stijn P.
Formato: Artigo
Idioma:Inglês
Publicado em: The Company of Biologists Ltd 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6361136/
https://ncbi.nlm.nih.gov/pubmed/30651296
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.166454
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